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| 2007 |
| Sloter, E, Marchetti, F, Eskenazi, B, Nath, J, Weldon, RH, Wyrobek, AJ, Cabreros, D. Frequency of Human Sperm Carrying Structural Aberrations of Chromosome 1 Increases with Advancing Age. Fertil Steril 87(5):1077-86, May 2007. |
| Doull, J, Borzelleca, JF, Becker, R, Daston, G, DeSesso, J, Fan, A, Fenner-Crisp, P, Holsapple, M, Holson, J, Llewellyn, GC, MacGregor, J, Seed, J, Walls, I, Woo, Y, Olin, S. Framework for Use of Toxicity Screening Tools in Context-Based Decision-Making. Food and Chemical Toxicology 45 759-796, 2007. |
| Faber, WD, Deyo, JA, Stump, DG, Ruble, K. Two-Generation Reproduction Study of Di-2-Ethylhexyl Terephthalate in Crl:CD Rats. Birth Defects Research (Part B) 80:69-81, 2007. |
| Siddiqui, WH, Stump, DG, Plotzke, KP, Holson, JF, Meeks, RG. A Two-Generation Reproductive Toxicity Study of Octamethylcyclotetrasiloxane (D4) in Rats Exposed by Whole-Body Vapor Inhalation. Reproductive Toxicology 23 202-215, 2007. |
| Meeks, RG, Stump, DG, Siddiqui, WH, Holson, JF, Plotzke, KP, Reynolds, VL. An Inhalation Reproductive Toxicity Study of Octamethylcyclotetrasiloxane (D4) in Female Rats Using Multiple and Single Day Exposure Regimens. Reproductive Toxicology 23 192-201, 2007. |
| Siddiqui, WH, Stump, DG, Reynolds, VL, Plotzke, KP, Holson, JF, Meeks, RG. A Two-Generation Reproductive Toxicity Study of Decamethylcyclopentasiloxane (D5) in Rats Exposed by Whole-Body Vapor Inhalation. Reproductive Toxicology 23 216-225, 2007. |
| Faber, WD, Roberts, LSG, Stump, DG, Beck, M, Kirkpatrick, D, Regan, KS, Tort, M, Moran, E, Banton, M. Inhalation Developmental Neurotoxicity Study of Ethylbenzene in Crl-CD Rats. Birth Defects Research (Part B) 80:34-48, 2007. |
| Sved, DW, Godsey, JL, Ledyard, SL, Mahoney, AP, Stetson, PL, Ho, S, Myers, NR, Resnis, P, Renwick, AG. Absorption, Tissue Distribution, Metabolism and Elimination of Taurine Given Orally to Rats. Amino Acids 32(4): 459-466, 2007. |
| Teiber, JF, Billecke, SS, LaDu, BN, Draganov, DI. Estrogen Esters as Substrates for Human Paraoxonases. Archives of Biochemistry and Biophysics 2007 (in press). |
| 2006 |
| Soloviev, MV, Hamlin, RL, Barrett, RM, Chengelis, CP, Schaefer, GJ. Different Species Require Different Correction Factors For the QT Interval. Cardiovascular Toxicology 06 145-157, 2006. |
| Sands, SA, DiRienzo, MA, Eapen, AK, Harris, WS. Stearidonic Acid Increases Red Blood Cell and Cardiac Levels of EPA, but not DPA or DHA, in Dogs. FASEB J., 2006. |
| Sloter E, Schmid T, Marchetti F, Eskenazi B, Nath J, Wyrobek AJ. Quantitative Effects of Male Age on Sperm Motion. Submitted for Publication to Fertility and Sterility, 2006. |
| Bowman, CJ. Book review: Naz, RK., Endocrine Disruptors: Effects on the Male and Female Reproductive Systems, Second Edition. Veterinary Pathology 43:395, CRC Press, Boca Raton, FL, 2006 |
| Soloviev MV, Hamlin RL, Shellhammer LJ, Barrett RM, Wally RA, Birchmeier PA, Schaefer GJ. Variations in Hemodynamic Parameters and ECG in Healthy Conscious Freely Moving Telemetrized Beagle Dogs. Cardiovascular Toxicology 6(1):51-52, 2006. |
| 2005 |
| Meeks, RG, Jean, PA, Mertens, JJWM, Regan, KS, Crissman, JW, Plotzke, KP. Chronic Toxicity and Oncogenicity Study of Polydimethylsiloxane (PDMS) 10 CST Fluid in Fischer 344 Rats. The Toxicologist 84 1510, 2005. |
| McKee, RH, Pavkov, KL, Trimmer, GW, Keller, LH, Stump, DG. Developmental and Reproductive Toxicity of Di-isoheptyl Phthalate in Rodents. The Toxicologist 84 275, 2005. |
| Nuber, DC, Weiner, ML, Harriman, JF, Cohen, SM. A 90-Day Dietary Study on Carrogeenan With Emphasis on the Gastrointestinal Tract. The Toxicologist 84 1397, 2005. |
| Cruzan, G, Faber, WD, Johnson, KA, Roberts, LS, Hellwig, J, Carney, E, Yarrington, JT, Stump, DG. Two-Generation Reproduction Study of Styrene by Inhalation in Crl-CD Rats. Birth Defects Research (Part B) 74:211-220, 2005. |
| Bowman, CJ, Turner, KJ, Sar, M, Barlow, NJ, Gaido, KW, Foster, PMD. Altered Gene Expression in Developing Wolffian Ducts from Rats Following di(n-butyl) phthalate Exposure. Toxicological Sciences 86(1) 161-174, 2005. |
| Eskenazi, B, Kidd, SA, Marks, AR, Sloter, E, Block, G, Wyrobek, AJ. Antioxidant Intake is Associated With Semen Quality in Healthy Men. Hum Reprod 20(4):1006-12, 2005. |
| Holson, JF, Stump, DG, Pearce, LB, Watson, RE, DeSesso, JM. Mode of Action: Yolk Sac Poisoning and Impeded Histiotrophic Nutrition – HBOC-Related Congenital Malformations. Critical Reviews in Toxicology 35:739-745, 2005. |
| Parker, GA, Picut, C. Liver Immunobiology. Toxicologic Pathology 33: 52-62, 2005. |
| Cruzan, G, Faber, WD, Johnson, KA, Roberts, LS, Hellwig, J, Maurissen, J, Beck, MJ, Radovsky, A, Stump, DG. Developmental Neurotoxicity Study of Styrene by Inhalation in Crl-CD Rats. Birth Defects Research (Part B) 74: 221-232, 2005. |
| Beck, MJ, Nemec, MD, Kirkpatrick, DT, Holson, JF, Lewis, SA, Piccirillo, VJ, McAllister, D. A Method for Simultaneous Whole-Body Inhalational (Inh.) Exposure of Lactating Rats and Offspring. (in press 2005). |
| 2004 |
| Varsho, BJ, Edwards, RJ, Obringer, DJ, Bowman, CJ, Stump, DG, Nemec, MD. An Analysis of Pregnancy Rates from Prenatal Developmental Toxicity Studies in Artificially Inseminated HRA:(NZW)SPF Rabbits Conducted in an Eight-Year Period. Presented at the Teratology, Vancouver, CANADA. June, 2004. |
| Pruett, SB, Padgett, EL. Thymus-Derived Glucocorticoids are Insufficient for Normal Thymus Homeostasis in the Adult Mouse. BMC Immunology, 5:24, 2004. |
| Padgett, EL. A U.S. Perspective on the Off-Label Use, Regulatory History and Development of Drugs in the Pediatric Population. Safety Evaluation Form, Dokusei Shitsumon Bako, Scientist Inc. 7:14-30, 2004. |
| Harriman, JF, Schnellmann, RC. Mechanisms of Cell Death. Toxicology of the Kidney, 3rd Edition, J Tarloff and L Lash, eds. 2004. |
| Cruzan, G, Corley, RA, Hard, GC, Mertens, JJWM, McMartin, KE, Snellings, WM, Gingell R, Deyo, JA. Subchronic Toxicity of Ethylene Glycol in Wistar and F-344 Rats Related to Metabolism and Clearance of Metabolites. Toxicol. Sci. 81 502-511, 2004. |
| Czarneski, J, Lin, YC, McCarthy, B, Fernandez, H, Parker, G, Mansour, A, Huppi, K, Marti, G, Raveche, E. Studies in NZB IL-10 knockout mice of the requirement of IL-10 for progression of B-cell lymphoma. Leukemia 18 597-606, 2004. |
| Beck, MJ, Ching, SV, Leung, E, Moorman, AR, Lai, AA, Radovsky, A, Buelke-Sam, J. An Acute Toxicity and Pharmacokinetic Study of the ACE inhibitor, ramipril (R), in Juvenile Rats. Birth Defects Res. Part A. Clin. Molecular Teratol 70 294, 2004. |
| Schmid TE, Brinkworth MH, Hill F, Sloter E, Kamischke A, Marchetti F, Nieschlag E, Wyrobek AJ. Detection of Structural and Numerical Chromosomal Abnormalities by ACM-FISH Analysis in Sperm of Oligozoospermic Infertility Patients. Human Reprod 19(6):1395-400, 2004. |
| Sloter E, Nath J, Eskenazi B, Wyrobek AJ. Effects of Male Age on the Frequencies of Germinal and Heritable Chromosomal Abnormalities in Humans and Rodents. Fertil Steril 81:925-943, 2004. |
| 2003 |
| Gleason, TG1, Chengelis, CP1, Jackson, CB1, Lindstrom, P2, 1WIL Research Laboratories, Inc., Ashland, OH, 2Maxim Pharmaceuticals, San Diego, CA. A 24-Hour Continuous Infusion Study of Bivalirudin in the Rat. International Journal of Toxicology 22-3; 195, 2003. |
| Burns-Naas, LA, Holson, JF. Absence of Embryo-Fetal Toxicity in Rats or Rabbits Following Oral Dosing with Nelfinavir. Regulatory Toxicology and Pharmacology 38/3, 291-303, 2003. |
| Burns-Naas, LA, Holson, JF. Absence of Reproductive and Developmental Toxicity in Rats Following Oral Dosing with Nelfinavir. Regulatory Toxicology and Pharmacology 38/3, 304-316, 2003. |
| Harriman, JF, Padgett, EL, Kirkpatrick, DT, Haas, MC, Wilkinson, JT, Chengelis, CP. Caloric Restriction Reduces Body Fat, Lean Muscle Mass, and Palpable Masses while Increasing the 24-Month Survival Rate in Sprague-Dawley Rats. The Toxicologist 72 (S-1), 2003. |
| Schaefer, GJ, Kirkpatrick, DT, Holson, JF, Chengelis, CP, Regan, KS, Piccirillo, VJ. A Six-Week Inhalation Neurotoxicity Study of Methyl Bromide in Dogs. The Toxicologist 72 (S-1), 2003. |
| Harriman, JF, Schnellmann, RG. Mechanisms of Cell Death. Toxicology of the Kidney, 3rd Edition. J. Tarloff and L. Lash, eds. 2003 (in preparation). |
| Bu, W, Myers, N, McCarty, JD, O’Neill T, Holler, S, Stetson, PL, Sved, DW. Simultaneous Determination of Six Urinary Porphyrins Using Liquid Chromatography - Tandem Mass Spectrometry. Journal of Chromatography B 783 411-423, 2003. |
| 2002 |
| Schaefer, GJ, Nemec, MD, Herberth, MT, Pitt, JA, Radovsky, AE, Knapp, JF. Validation of Developmental Neurotoxicity Endpoints in Rats Administered Methimazole in Drinking Water. The Toxicologist 66:234, 2002. |
| Chengelis, CP, Padgett, EL, Rhodes, KK, Frey, R, Simons, MW, Schaefer, GJ. Performance Validation and Demonstration of the Sensitivity to Detect Drug Induced Alterations Using a Locomotor Activity System for Large Animals. The Toxicologist 66:263, 2002. |
| Beck, MJ, Nemec, MD, Schaefer, GJ, Stump, DG, Buelke-Jon, J. Validation of Peripheral Tissue Cholinesterase Activity Assessment in Rats Administered Chlorpyrifos by Gavage. Teratology 65:p5, 2002. |
| Cappon, GD, Stump, DG. Developmental Neurotoxicity: What Have We Learned from Guideline Studies? Handbook of Neurotoxicology Volume II, pp 81-109, 2002. Editor: Massaro, E.J., Humana Press, Totowa, NJ. |
| Harriman, JF, Liu, X, Aleo, MD, Machaca, K, Schnellmann, RG. Endoplasmic Reticulum Ca2+ Signaling and Calpains Mediate Renal Cell Death. Cell Death and Differentiation 9: 734-741, 2002. |
| Behringer, W, Safar, P, Kentner, R, Wu, X, Kagan, VE, Radovsky, A, Clark, RS, et al. Antioxidant Tempol Enhances Hypothermic Cerebral Preservation During Prolonged Cardiac Arrest in Dogs. J Cereb Blood Flow Metab 22:105-117, 2002. |
| Schaefer, GJ, Nemec, MD, Herberth, MT, Pitt, JA, Radovsky, AE, Knapp, JF. Validation of Developmental Neurotoxicity Endpoints in Rats Administered Methimazole in Drinking Water. The Toxicologist (Suppl.) 66:1144, 2002. |
| Capen, CC, DeLellis, RA, Yarrington, JT. Endocrine System. Handbook of Toxicologic Pathology 2nd Edition. Vol. 2, chapter 21, pgs. 681-783, 2002. W.H. Haschek–Hock, C.G. Rousseaux and M.A. Wallig, Editors. Academic Press, San Diego. |
| Beck, MJ, Nemec, MD, Schaefer, GJ, Stump, DG, Buelk-Sam. Validation of Peripheral Tissue Cholinesterase Activity Assessment in Rats Administered Chlorpyrifos by Gavage. Teratology Society, 2002. |
| Padgett, EL, Seelig, LL, Jr. Effects on T-Cell Maturation and Proliferation Induced by Lactational Transfer of Cyclosporine to Nursing Pups. Transplantation 73:867-874, 2002. |
| Pitt, JA, Snyder, LT, Smith, BL, Varsho, BJ, Nemec, MD, Holson, JF. An X-Ray Study of the Incidence of Supernumierary Ribs and Presacral Vertebrae in Adult Rats, Mice and Rabbits. Teratology 65:3258, 2002. |
| Liu, X, Harriman, JF, Schnellmann, RG. Cytoprotective Properties of Novel Non-Peptide Calpain Inhibitors in Renal Cells. J Pharmacol Exp Ther 302:88-94, 2002. |
| Beck, BD, Slayton, TM, Farr, CH, Sved, DW, Crecelius, EA, Holson, JF. Systemic Update of Inhaled Arsenic in Rabbits. Human and Experimental Toxicology 21: 205-215, 2002. |
| 2001 |
| Schaefer, GJ, Wilkinson, JT, Chengelis, CP. A Comparison of Heart Rate and Blood Pressure Changes in Dogs and Rats Produced by the Oral Administration of Isoproterenol and Propranolol. The Toxicologist 60:15, 2001. |
| Yarrington, JT, Rosol, TJ, Latandress, J, Capen, CC. Adrenal Gland: Structure, Function, Mechanisms of Toxicity. Toxicol Pathology 29:41-48, 2001. |
| Liu, X, Rainey, JJ, Harriman, JF, Schnellmann, RG. Calpains Mediate Acute Renal Cell Death: Role of Autolysis and Translocation. Am J Physiol 281:F728-F738, 2001. |
| Harriman, JF, Schnellmann, RG. The Role of Calcium and Calpains in Renal Proximal Tubular Cell Death. Dissertation, University of Arkansas for Med. Sciences, 2001. |
| Cragin, DW, Mertens, JJWM, Yarrington, JT, Salmona, M, Ciocca, P, Bui, QQ. Absence of Neurotoxicity for Tricyclohexyltin Hydroxide in a 90-Day Feeding Study in Rats. Poster presented at the American College of Toxicology Meeting in Washington, DC, November 4-7, 2001. |
| Varsho, BJ, Stump, DG, Becker, RA, Owens, JW. OECD Rodent Uterotrophic Assay Validation Variables: Blinded Administration, Animal Model, and Route of Administration. Toxicol. Sci. 60:295-296, 2001. |
| Yarrington, JT, Capen, CC. Changes in the Structure and Function of the Adrenal Gland. Pathobiology of the Aging Dog Vol. 1, pgs. 273-284, 2001. Iowa State University, Ames. |
| 2000 |
| Stump, DG, Holson, JF, Clevidence, KJ, Knapp, JF, Farr, CH. Evaluation of the Prenatal Developmental Toxicity of Orally Administered Arsenic Trioxide in Rats. Food and Chemical Toxicology 38:459-466, 2000. |
| Stump, DG, Nemec, MD, Pitt, JA, Shoup, DA, Glenn, G, Rhodes, K. Effect of Propylthioracil (PTU) on Developmental Neurotoxicity Endpoints in Crl:CD (SD)IGS BR Rats. Biological Reference Data on CD(SD) IGS Rats, 2000. Best Printing Co. Ltd., Tokyo. |
| Padgett, EL, Sibley, DA, Jerrells, TR. Effect of Adrenalectomy on Ethanol-Associated Changes in Lymphocyte Cell Numbers and Subpopulations in Thymus, Spleen and Gut-Associated Lymphoid Tissue. International Journal of Immunopharmacology 22:265-298, 2000. |
| Stetson, P, Draganov, D, Watson, C, Billecke, S, La Du, B. Rabbit Serum Paraxonase 3 (PON3) Is a High Density Lipoprotein-associated Lactonase and Protects Low Density Lipoprotein Against Oxidation. The American Society for Biochemistry and Molecular Biology, Inc. Vol. 275, No. 43. pgs. 33435-33442, 2000. |
| Varsho, BJ, Cappon, GD, Kirkpatrick, DT, Welter, DC, Obrecht, JC, Feikert, TD. A Study of the Effects of Restraint Duration for Nose-Only Inhalation Exposure on Embryo/Fetal Development in Rats. Toxicol. Sci. 54:204, 2000. |
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