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General Toxicology

WIL Research has provided general toxicology services since 1976. Our experienced scientific staff has conducted thousands of toxicity studies for the pharmaceutical, biotechnology, chemical, agricultural, veterinary, and food and consumer products industries. Our services include a complete spectrum of studies from single dose to carcinogenicity, employing all standard laboratory animal species and routes of administration.

Our experienced scientific staff can provide guidance for successful execution of nonclinical laboratory studies, timely regulatory submissions and can assist with requirements in risk assessment and product development programs.

Capabilities

General

Good Laboratory Practice (GLP) compliant
EPA, FDA, OECD, ICH, MAFF, EU, MHLW experience
Complete range of studies
Acute (including eye and skin irritation and sensitization)

Routine and specialized routes of administration include:

Oral
Inhalation
Diet and drinking water
Subcutaneous
Intravenous injection
Infusion
Percutaneous
Dermal
Ocular
Vaginal
Rectal
Urinary bladder catheterization
Customized routes of administration (Intraventricular)
Surgical models

Support Operations

Pharmacy / Formulations Laboratory
Analytical and bioanalytical chemistry laboratory
Pathology and veterinary medicine staff
Clinical pathology laboratory
Histology laboratory
Necropsy
Automated computerized data collection and management systems (WTDMS™)
Specialized report preparation staff
Comprehensive Quality Assurance Unit monitoring

Special Services

Consulting
Special projects in support of litigation
Custom risk assessment projects

Experienced with all standard rodent and non-rodent laboratory animals including NHP.